Revista Portuguesa de Pneumologia Revista Portuguesa de Pneumologia
Rev Port Pneumol 2017;23:280-6 - Vol. 23 Num.5 DOI: 10.1016/j.rppnen.2017.04.008
Original article
The frequency of lung cancer in patients with pulmonary hamartomas: An evaluation of clinical, radiological, and pathological features and follow-up data of 96 patients with pulmonary hamartomas
G.H. Ekincia,, , O. Hacıömeroğlua, A. Ersevb, L. Alpayc, H. Özgena, A. Yılmaza
a Department of Pulmonology, Süreyyapaşa Chest Diseases and Thoracic Surgery Training and Research Hospital, Maltepe, İstanbul, Turkey
b Department of Pathology, Süreyyapaşa Chest Diseases and Thoracic Surgery Training and Research Hospital, Maltepe, İstanbul, Turkey
c Department of Thoracic Surgery, Süreyyapaşa Chest Diseases and Thoracic Surgery Training and Research Hospital, Maltepe, İstanbul, Turkey
Received 19 October 2016, Accepted 25 April 2017
Abstract
Purpose

To investigate the frequency of lung cancer in patients with pulmonary hamartomas and to evaluate clinical, radiological, and pathological characteristics of pulmonary hamartomas.

Basic procedures

We reviewed pathology records of pulmonary hamartomas diagnosed between 2003 and 2014. Medical records and the hospital electronic database were also reviewed for each patient to obtain clinical, radiological, and pathological characteristics of pulmonary hamartomas and accompanying malignancies.

Main findings

Ninety-six patients with pulmonary hamartomas were identified. There were 26 females (27%) and 70 males (73%), with a mean age of 56.2 years (range 22–87 years). Malignancies were detected in 23 patients (24%), which developed previously in five patients (1 synchronous, 4 metachronous lesions), and concomitantly in 18 patients (with origin from the lung in 17 patients and from the pleura in 1 patient).

Principal conclusions

Our results show that patients with pulmonary hamartomas may have coexisting lung malignancies.

Keywords
Hamartoma, Lung neoplasms, Diagnosis
Rev Port Pneumol 2017;23:280-6 - Vol. 23 Num.5 DOI: 10.1016/j.rppnen.2017.04.008